24(S),25-epoxy Cholesterol
24(S),25-epoxy Cholesterol
24(S),25-epoxy Cholesterol is an oxysterol and the most abundant oxysterol in mouse ventral midbrain.{43943} It activates liver X receptors (LXRs)...
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€146.00 €124.10
15-deoxy-?12,14-PGD2 is a metabolite of PGD2 (Item No. 12010).{11797} It is an agonist of PGD2 receptor 2 (DP2) that binds DP2 (Ki = 50 nM for the mouse receptor expressed in HEK293 cell membranes) and induces activation of eosinophils (EC50 = 8 nM).{11399,11055} It also stimulates the recruitment of steroid receptor coactivator-1 (SRC-1) to peroxisome proliferator-activated receptor ? (PPAR?) and induces PPAR?-mediated transcription in a reporter assay when used at a concentration of 5 µM.{11797} 15-deoxy-?12,14-PGD2 is cytotoxic to L1210 murine leukemia cells (IC50 = 0.3 µg/ml).{1424} It inhibits ADP-induced platelet aggregation (IC50 = 320 ng/ml) less potently than PGD2.{1139}
Territorial Availability: Available through Bertin Technologies only in France
| Size | 1 mg, 5 mg, 500 µg |
|---|---|
| Shipping | dry ice |
| CAS number | 85235-11-6 |
| Molecular formula | C20H30O4 |
| Smiles | O=C1/C([C@@H](C/C=CCCCC(O)=O)[C@@H](O)C1)=C/C=C/CCCCC, O=C1/C([C@@H](C/C=CCCCC(O)=O)[C@@H](O)C1)=C/C=C/CCCCC, O=C1/C([C@@H](C/C=CCCCC(O)=O)[C@@H](O)C1)=C/C=C/CCCCC |
| Molecular weight | 334,5 |
| Custom code | 2937.50 |
| Formulation | A solution in methyl acetate |
| Purity | ≥95% |
| UNSPSC code | 12352100 |
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