GSK-<wbr/>J2 (sodium salt)

GSK-J2 (sodium salt)

CAT N°: 12056
Price:

From 54.00 45.90

The histone H3 lysine 27 (H3K27) demethylase JMJD3 plays important roles in the transcriptional regulation of cell differentiation, development, the inflammatory response, and cancer.{19496,19494} GSK-J2 is a pyridine regio-isomer of GSK-J1 which poorly inhibits JMJD3 (IC50 > 100 ?M), making it an appropriate negative control for in vitro studies involving GSK-J1.{21388} For in vivo research, cell-permeable prodrug forms of GSK-J1 and GSK-J2 are available as GSK-J4 (Item No. 12073) and GSK-J5 (Item No. 12074), respectively. See the Structural Genomics Consortium (SGC) website for more information.

We also advise you