8-<wbr/>CPT-<wbr/>Cyclic AMP (sodium salt)

8-CPT-Cyclic AMP (sodium salt)

CAT N°: 12011
Price:

From 85.00 72.25

8-CPT-Cyclic AMP is a lipophilic activator of the cyclic-AMP- and cyclic-GMP-dependent protein kinases, PKA and PKG (Ka = 0.05 and 0.11 ?M, respectively).{22886} 8-CPT-cAMP inhibits cyclic GMP-specific phosphodiesterase (PDE VA), cyclic GMP-inhibited phosphodiesterase (PDE III), and cyclic AMP-specific phosphodiesterase (PDE IV) with IC50 values of 0.9, 24, and 25 ?M, respectively.{22887} It has been used in studies to analyze the signal transduction pathways initiated by cyclic-AMP- and cyclic-GMP-dependent protein kinases.

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 8-[(4-chlorophenyl)thio]-cyclic 3′,5′-(hydrogen phosphate)-adenosine, monosodium salt
  • Correlated keywords
    • 41941-66-6 cyclic-AMP-dependent kinases cyclic-GMP-dependent proteins PKAs PKGs inhibitors activators phosphodiesterases PDE VA cGMP PDE III cAMP PDE IV signals signaling transductions PDEs cyclics AMPs cAMP cGMP lipophilic acitvators cells permeables analogs CPT GMP pathways sodium salts Na+ inhibits inhibitors cAMP-dependent dependents cGMP-dependent cAMP-specific cGMP-specific cAMP-inhibited cGMP-inhibited inhibited specific
  • Product Overview:
    8-CPT-Cyclic AMP is a lipophilic activator of the cyclic-AMP- and cyclic-GMP-dependent protein kinases, PKA and PKG (Ka = 0.05 and 0.11 ?M, respectively).{22886} 8-CPT-cAMP inhibits cyclic GMP-specific phosphodiesterase (PDE VA), cyclic GMP-inhibited phosphodiesterase (PDE III), and cyclic AMP-specific phosphodiesterase (PDE IV) with IC50 values of 0.9, 24, and 25 ?M, respectively.{22887} It has been used in studies to analyze the signal transduction pathways initiated by cyclic-AMP- and cyclic-GMP-dependent protein kinases.

We also advise you