Bacopasaponin C

Bacopasaponin C

CAT N°: 11820
Price:

140.00 119.00

Bacopasaponin C is a triterpenoid saponin originally isolated from B. monniera that has diverse biological activities.{48521,48522,48523} It inhibits the ATPase activity of P-glycoprotein (IC50 = 57.83 µg/ml).{39064} Bacopasaponin C inhibits scopolamine-induced impairments in spatial memory in the Morris water maze and memory retrieval in the step-down test in mice when administered at a dose of 50 mg/kg.{48521} It also decreases the time mice spent immobile in the forced swim and tail suspension tests, indicating antidepressant-like activity.{48522} Bacopasaponin C reduces the spleen parasite load in a hamster model of leishmaniasis when administered as a free compound or in liposomal, niosomal, microencapsulated, or nanocapsulated forms.{48523}

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