Zearalenone

Zearalenone

CAT N°: 11353

Zearalenone is a mycotoxin that has been found in Fusarium and has estrogenic activities.{20562} It binds to human estrogen receptor ? (ER?) and ER? (IC50s = 9 and 5.8 nM, respectively).{54526} Zearalenone induces precocious development of mammary tissues in young female pigs and prepucial enlargement in young male pigs.{20560} Zearalenone (1.5-5 mg/kg of diet) induces hyperestrogenism in pigs. It also induces degeneration of meiotic chromatin in oocytes and reduces fertility in pigs when administered at a dose of 200 µg/kg.{20561} Zearalenone has been found as a contaminant in wheat, maize, and barley and livestock feeds.{20560,20561}

Territorial Availability: Available through Bertin Technologies only in France

Technical Warning: Bertin Technologies restricts the sale of this product to licensed controlled substance laboratories and qualified academic research institutions. Please contact us for further details.

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  • Synonyms
    • (3S,11E)-3,4,5,6,9,10-hexahydro-14,16-dihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1,7(8H)-dione
  • Correlated keywords
    • 18695-28-8 mycotoxins estrogen receptors, hormones fertility reproduction abortion infertility fungi food animal feeds trans-zearalenone zearalenon
  • Product Overview:
    Zearalenone is a mycotoxin that has been found in Fusarium and has estrogenic activities.{20562} It binds to human estrogen receptor ? (ER?) and ER? (IC50s = 9 and 5.8 nM, respectively).{54526} Zearalenone induces precocious development of mammary tissues in young female pigs and prepucial enlargement in young male pigs.{20560} Zearalenone (1.5-5 mg/kg of diet) induces hyperestrogenism in pigs. It also induces degeneration of meiotic chromatin in oocytes and reduces fertility in pigs when administered at a dose of 200 µg/kg.{20561} Zearalenone has been found as a contaminant in wheat, maize, and barley and livestock feeds.{20560,20561}

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