PGDM-<wbr/>d<sub>4</sub>

PGDM-d4

CAT N°: 11344
Price:

From 266.00 226.10

Prostaglandin DM (PGDM)-d4 contains four deuterium atoms at the 18, 18′, 19 and 19′ positions. It is intended for use as an internal standard for the quantification of PGDM by GC- or LC-mass spectrometry. PGD2 plays a pharmacological role in allergic and asthmatic anaphylaxis, normal physiological sleep and lowering of body temperature, as well as inhibits platelet aggregation and relaxes vascular smooth muscle.{580} PGDM is a major urinary metabolite of PGD2 with a unique lower sidechain that readily undergoes reversible cyclization.{35} It is used as a biomarker to assess endogenous production of PGD2.

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