JWH 073 N-<wbr/>(4-<wbr/>hydroxybutyl) metabolite-<wbr/>d<sub>5</sub>

JWH 073 N-(4-hydroxybutyl) metabolite-d5

CAT N°: 10934
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JWH 073 N-(4-hydroxybutyl) metabolite-d5 (Item No. 10934) is intended for use as an internal standard for the quantification of JWH 073 N-(4-hydroxybutyl) metabolite (Item No. 9000865) by GC- or LC-MS. JWH 073 is a mildly selective agonist of the central cannabinoid (CB1) receptor derived from the aminoalkylindole WIN 55,212-2. The Ki values for binding CB1 and the peripheral cannabinoid (CB2) receptor are 8.9 and 38 nM, respectively for a CB1:CB2 ratio of 0.23.{16797} JWH 073 is one of several synthetic CBs which have been included in smoking mixtures. JWH 073 N-(4-hydroxybutyl) metabolite is expected to be a major urinary metabolite of JWH 073, characterized by monohydroxylation of the N-alkyl chain, based on the metabolism of the closely-related JWH 015 and JWH 018.{18292,18291} In urine samples, this metabolite of JWH 018 is almost completely glucuronidated.{18291}

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