JWH 200-<wbr/>d<sub>5</sub>

JWH 200-d5

CAT N°: 10903
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JWH 200-d5 contains five deuterium atoms at the 2′, 4′ ,5′, 6′, and 7′ positions. It is intended for use as an internal standard for the quantification of JWH 200 by GC- or LC-mass spectrometry. JWH 200 is an aminoalkylindole that acts as a cannabinoid (CB) receptor ligand. It binds to the CB1 receptor with high-affinity (IC50 = 7.8-42 nM).{16961,16684} The effects of JWH 200 in locomotor activity, tail-flick latency, hypothermia, and ring-immobility tests are comparable or superior to ?9-THC or WIN 55,212.{16963} It potently inhibits the contraction of electrically-stimulated mouse vas deferens (IC50 = 3.7-6.0 nM).{16960,16962}

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