Maresin 1

Maresin 1

CAT N°: 10878
Price:

116.00 98.60

Maresin 1 is a member of the specialized pro-resolving mediator (SPM) family of bioactive lipids.{27956} It is produced from docosahexaenoic acid (DHA; Item Nos. 90310 | 17950) in human peripheral blood mononuclear cells (PBMCs). Maresin 1 (100 nM) reduces TNF-?-induced increases in reactive oxygen species (ROS) in primary human vascular smooth muscle and endothelial cells.{28026} It decreases disease severity, neutrophil infiltration, and intestinal crypt damage in a mouse model of colitis induced by dextran sulfate (DSS; Item No. 23250) when administered at doses of 0.3 and 1 µg/animal.{28042} Maresin 1 (0.1, 1, and 10 ng/animal) inhibits increases in inflammatory exudate polymorphonuclear (PMN) neutrophil infiltration in a mouse model of peritonitis induced by zymosan A (Item No. 21175).{27956} It has been found in the synovial fluid of rheumatoid arthritis patients.{30501}

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