ABL 127

ABL 127

CAT N°: 10833
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From 55.00 46.75

ABL 127 is a covalent aza-?-lactam inhibitor of protein phosphatase methylesterase-1 (PME-1; IC50 = 4.2 nM).{19272} It selectively inhibits PME-1 over 50 other serine hydrolases in MDA-MB-231 and HEK293T cell lysates at 10 ?M. ABL 127 decreases proliferation of Ishikawa cells and migration of ECC-1 endometrial carcinoma cells when used at a concentration of 50 nM.{42730}

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