4-<wbr/>hydroxy Nonenal Glutathione (trifluoro<wbr/>acetate salt)

4-hydroxy Nonenal Glutathione (trifluoroacetate salt)

CAT N°: 10627
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From 99.00 84.15

4-hydroxy Nonenal Glutathione (HNE-GSH) is a major adduct formed by the reaction of 4-HNE with GSH.{18611,7334,18610,18731} 4-HNE-GSH levels in liver, plasma, or isolated cells can serve as biomarkers for oxidative stress.{18729} The trapping of 4-HNE by glutathione to give HNE-GSH prevents the formation of DNA adducts with 4-HNE.{1670,18730} In human polymorphonuclear leukocytes, HNE-GSH is metabolized to 1,4-dihydroxynonene glutathione (DHN-GSH), 4-hydroxynonenoic acid glutathione (HNA-GSH), and 4-hydroxy nonenal mercapturic acid (HNE-MA).{18611}

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