Etoricoxib

Etoricoxib

CAT N°: 10091
Price:

From 48.00 40.80

Etoricoxib is a dipyridinyl compound that demonstrates high in vitro and ex vivo selectivity for COX-2 over COX-1 in several assays, e.g., in the production of PGE2 by CHO cells expressing either COX-2 (IC50 = 79 nM) or COX-1 (IC50 > 50 µM).{11268,15425} Oral etoricoxib is well absorbed and metabolized extensively via oxidation, with metabolites excreted largely in the urine.{12837}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 5-chloro-6′-methyl-3-[4-(methylsulfonyl)phenyl]-2,3′-bipyridine
  • Correlated keywords
    • algix arcoxia etobrix etocox etosaid etoxib etropain kingcox MK0663 MK 663 MK663 nucoxia tauxib torcoxia L791,456 L791456 COX-2 COX2 dipyridinyl PGE-2 PG-E2 L-791456
  • Product Overview:
    Etoricoxib is a dipyridinyl compound that demonstrates high in vitro and ex vivo selectivity for COX-2 over COX-1 in several assays, e.g., in the production of PGE2 by CHO cells expressing either COX-2 (IC50 = 79 nM) or COX-1 (IC50 > 50 µM).{11268,15425} Oral etoricoxib is well absorbed and metabolized extensively via oxidation, with metabolites excreted largely in the urine.{12837}

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