Prostaglandin D Synthase (lipocalin-<wbr/>type; human) ELISA Kit

Prostaglandin D Synthase (lipocalin-type; human) ELISA Kit

CAT N°: 10007684
Price:

639.00 543.15

Prostaglandin D synthase (PGDS) catalyzes the isomerization of PGH2 to produce PGD2, a potent lipid mediator involved in sleep regulation, nociception, platelet aggregation, and allergic and inflammatory responses. Lipocalin-type PGDS (a.k.a. ?-trace) is a homodimer with each subunit ranging in size from 20-31 kDa, depending on the extent of glycosylation. L-PGDS has two functions: it catalyzes the conversion of PGH2 to PGD2 and acts as a carrier protein for lipid-like molecules (i.e., retinoids and thyroid hormones).{13130} L-PGDS is present in a variety of body fluids including cerebrospinal fluid, seminal fluid, and plasma. Cayman’s L-PGDS (human) ELISA is an immunometric (i.e., sandwich) ELISA with a standard curve ranging from 1.56-100 ng/ml and a limit of detection of 1.56 ng/ml. Inter- and intra-assay CV’s of less than 15% may be achieved at most concentrations. This assay has been validated using cerebrospinal fluid which contains approximately 12-30 µg/ml of L-PGDS.

Territorial Availability: Available through Bertin Technologies only in France

  • Correlated keywords
    • EIAs ELISAs Assays sandwich immunometric homodimer glycosylation catalyzes prostaglandins PGH2 PGD2 carrier proteins lipid-like molecules neurochemistry retinoids thyroid hormones body fluids cerebrospinal seminal plasma PTGDS beta-trace b-trace .beta.-trace betatrace btrace lpgds l-pgds assays
  • Product Overview:
    Prostaglandin D synthase (PGDS) catalyzes the isomerization of PGH2 to produce PGD2, a potent lipid mediator involved in sleep regulation, nociception, platelet aggregation, and allergic and inflammatory responses. Lipocalin-type PGDS (a.k.a. ?-trace) is a homodimer with each subunit ranging in size from 20-31 kDa, depending on the extent of glycosylation. L-PGDS has two functions: it catalyzes the conversion of PGH2 to PGD2 and acts as a carrier protein for lipid-like molecules (i.e., retinoids and thyroid hormones).{13130} L-PGDS is present in a variety of body fluids including cerebrospinal fluid, seminal fluid, and plasma. Cayman’s L-PGDS (human) ELISA is an immunometric (i.e., sandwich) ELISA with a standard curve ranging from 1.56-100 ng/ml and a limit of detection of 1.56 ng/ml. Inter- and intra-assay CV’s of less than 15% may be achieved at most concentrations. This assay has been validated using cerebrospinal fluid which contains approximately 12-30 µg/ml of L-PGDS.

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