FFAR1 (GPR40) Polyclonal Antibody

FFAR1 (GPR40) Polyclonal Antibody

CAT N°: 10007205
Price:

474.00 402.90

GPR40 is a seven transmembrane G Protein-coupled receptor with signalling mediated by medium- and long-chain fatty acids.{13140,13139} Found predominantly in the ?-cells of pancreatic islets, it has been implicated in the regulation of insulin secretion.{14194,14741} Overexpression of GPR40 in mouse ? cells leads to glucose intolerance suggesting a link between GPR40 expression and diabetes.{14194,14741} The receptor has also been identified as a possible mediator of oleate- and linoleate- stimulated proliferation of the human breast cancer cell line, MCF-7.{14742,13137} GPR40 has a calculated mass of 31.4 kDa bases on its amino acid sequence.

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