Glutathione Cell-<wbr/>Based Detection Kit (Blue Fluorescence)

Glutathione Cell-Based Detection Kit (Blue Fluorescence)

CAT N°: 600360
Price:

465.00 395.25

Glutathione (GSH) is the most prevalent low molecular-weight tripeptide thiol in animal cells. It serves as a primary cellular anti-oxidant and plays a fundamental role in the elimination of environmental toxins. During early apoptosis, cells may exclude GSH, causing a decrease in intracellular GSH levels. The intracellular level of GSH is thus used as an indicator of cell health. Cayman’s Cell-Based Glutathione Assay Kit (Blue Fluorescence) employs a cell-permeable dye, monochlorobimane (MCB), which reacts with GSH to generate a highly fluorescent product that can be measured using excitation and emission wavelengths of 380 and 480 nm, respectively. The kit can be easily adapted to screening programs for therapeutic compounds regulating intracellular GSH levels.

Territorial Availability: Available through Bertin Technologies only in France

  • Correlated keywords
    • kits assy kits measuring measurement glutathiones GSH tripeptides thiols animal cells oxygen radicals hydrogen peroxides H2O2 oxidative stress anti-oxidant antioxidents environmental toxins damages mitochondrial degeneration age-related aging apoptosis intracellular levels indicators cell-permeable dyes monochlorobimane MCB high-throughput screening
  • Product Overview:
    Glutathione (GSH) is the most prevalent low molecular-weight tripeptide thiol in animal cells. It serves as a primary cellular anti-oxidant and plays a fundamental role in the elimination of environmental toxins. During early apoptosis, cells may exclude GSH, causing a decrease in intracellular GSH levels. The intracellular level of GSH is thus used as an indicator of cell health. Cayman’s Cell-Based Glutathione Assay Kit (Blue Fluorescence) employs a cell-permeable dye, monochlorobimane (MCB), which reacts with GSH to generate a highly fluorescent product that can be measured using excitation and emission wavelengths of 380 and 480 nm, respectively. The kit can be easily adapted to screening programs for therapeutic compounds regulating intracellular GSH levels.

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