3-acetyl-11-keto-?-Boswellic Acid
3-acetyl-11-keto-?-Boswellic Acid
3-acetyl-11-keto-?-Boswellic acid is a naturally occurring pentacyclic triterpene isolated from the gum resin exudate from the stem of the tree...
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β-Boswellic acid is a pentacyclic triterpene originally isolated from Boswellia that has diverse bioactivities.{30044} It inhibits 5-lipoxygenase (5-LO) with an IC50 value of approximately 5 µM but is less potent than its derivative 3-acetyl-11-keto-β-boswellic acid (Item No. 11672).{6066} It inhibits cell proliferation in HL-60 cells with IC50 values of 3.7, 7.1, and 6.3 µM for DNA, RNA, and protein synthesis, respectively.{38153} In human umbilical vein endothelial cells (HUVECs) transiently deprived of oxygen and glucose, β-boswellic acid increases nitric oxide and increases phosphorylation of enzyme nitric oxide synthase (eNOS).{38155} It also increases calcium mobilization in platelets at concentrations ≥3 µM and induces platelet aggregation (EC50 = 8 µM).{38154}
Territorial Availability: Available through Bertin Technologies only in France
Size | 1 mg, 10 mg, 5 mg |
---|---|
Shipping | dry ice |
CAS Number | 631-69-6 |
Molecular Formula | C30H48O3 |
SMILES | O[C@@H]1CC[C@@]2(C)[C@](CC[C@]3(C)[C@]2([H])CC=C4[C@@]3(C)CC[C@]5(C)[C@@]4([H])[C@@H](C)[C@H](C)CC5)([H])[C@]1(C(O)=O)C |
Molecular Weight | 456,7 |
Formulation | A crystalline solid |
Purity | ≥95% |
Custom Code | 2918.99 |
UNSPSC code | 12352100 |
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3-acetyl-11-keto-?-Boswellic acid is a naturally occurring pentacyclic triterpene isolated from the gum resin exudate from the stem of the tree...
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View11-keto-?-Boswellic acid is a naturally occurring pentacyclic triterpene isolated from the gum resin exudate from the stem of the tree...
Viewα-Boswellic acid is a pentacyclic triterpene and an isomer of β-boswellic acid (Item No. 11693) originally isolated from B. serrata.{46214,46215}...
?-acetyl Boswellic acid is a pentacyclic triterpene and isomer of ?-acetyl-boswellic acid (Item No. 11674) originally isolated from B. serrata.{42584}...
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