5'-deoxy-5-<wbr/>Fluoro<wbr/>cytidine

5′-deoxy-5-Fluorocytidine

CAT N°: 10010682
Price:

94.00 79.90

5′-deoxy-5-Fluorocytidine is an intermediate metabolite of the DNA synthesis inhibitor capecitabine (Item No 10487).{18418} Capecitabine is converted by carboxylesterase to 5′-deoxy-5-fluorocytidine in the liver, then by cytidine deaminase to 5’-deoxy-5-fluorouridine in the liver and tumor tissues, and finally, by thymidine phosphorylase to 5-fluorouracil (Item No. 14416) in tumors.{18418} The cytotoxicity of this intermediate occurs only after conversion to 5-fluorouracil.{18418}

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