CB-<wbr/>13

CB-13

CAT N°: 10010398
Price:

From 82.00 69.70

CB-13 is a dual agonist of the CB1 (IC50 = 15 nM) and CB2 (IC50 = 98 nM) receptors.{14984} In rats, oral CB-13 (3 mg/kg) potently blocks CB1-dependent neuropathic mechanical hyperalgesia, shows limited brain penetration, and exhibits good oral bioavailability.{14984} CB-13 does not possess genotoxic potential, as indicated by negative results in both chromosome aberration and reverse mutation assays.{14984} The effects of CB-13 on other aspects of CB signaling have not been assessed.

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 1-naphthalenyl[4-(pentylox)-1-naphthalenyl]-methanone
  • Correlated keywords
    • cannabinoids CB1 CB2 central peripheral receptors agonists pains hyperalgesia blocks blocking CB13 CB 13 CRA13 CRA 13 analytical references standards
  • Product Overview:
    CB-13 is a dual agonist of the CB1 (IC50 = 15 nM) and CB2 (IC50 = 98 nM) receptors.{14984} In rats, oral CB-13 (3 mg/kg) potently blocks CB1-dependent neuropathic mechanical hyperalgesia, shows limited brain penetration, and exhibits good oral bioavailability.{14984} CB-13 does not possess genotoxic potential, as indicated by negative results in both chromosome aberration and reverse mutation assays.{14984} The effects of CB-13 on other aspects of CB signaling have not been assessed.

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