5-<wbr/>Iodotubercidin

5-Iodotubercidin

CAT N°: 10010375
Price:

83.00 70.55

5-Iodotubercidin is an inhibitor of adenosine kinase (IC50 = 0.026 µM).{66198} It inhibits protein kinase A (PKA), phosphorylase kinase, casein kinase 1 (CK1), CK2, and PKC (IC50s = 5-10, 5-10, 0.4, 10.9, and 0.4 µM, respectively).{15083} 5-Iodotubercidin is also an inhibitor of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA-dependent RNA polymerase (RdRp; EC50 = 0.75 µM).{62876} It decreases fatty acid synthesis and increases fatty acid oxidation in isolated rat hepatocytes when used at a concentration of 20 µM.{15219} In vivo, 5-iodotubercidin reduces the number of seizures in a rat model of seizures induced by maximum electroshock (MES; ED50 = 6 mg/kg).{66198}

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