Kenpaullone

Kenpaullone

CAT N°: 10010239
Price:

From 74.00 62.90

The development of selective, cell-permeable protein kinase inhibitors for the treatment of cancer, inflammation, and other diseases, is a major focus of drug development efforts. Kenpaullone is an ATP-competitive inhibitor of several cyclin-dependent kinases (CDKs) as well as glycogen synthase kinase 3? (GSK3?).{14993,14995,14994} It inhibits GSK3? with an IC50 value of 0.23 µM and Cdk1/cyclin B, Cdk2/cyclin A, Cdk5/p25, and lymphocyte kinase with IC50 values of 0.4, 0.68, 0.85, and 0.47 µM, respectively.{14995,14993}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 9-bromo-7,12-dihydro-indolo[3,2-d][1]benzazepin-6(5H)-one
  • Correlated keywords
    • GSK-3.beta. cyclin-dependent kinase cyclin CDKs inhibitors inhibits inhibition proliferations cell cycle cancers
  • Product Overview:
    The development of selective, cell-permeable protein kinase inhibitors for the treatment of cancer, inflammation, and other diseases, is a major focus of drug development efforts. Kenpaullone is an ATP-competitive inhibitor of several cyclin-dependent kinases (CDKs) as well as glycogen synthase kinase 3? (GSK3?).{14993,14995,14994} It inhibits GSK3? with an IC50 value of 0.23 µM and Cdk1/cyclin B, Cdk2/cyclin A, Cdk5/p25, and lymphocyte kinase with IC50 values of 0.4, 0.68, 0.85, and 0.47 µM, respectively.{14995,14993}

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