1-Stearoyl-2-<wbr/>Arachidonoyl-<wbr/>d<sub>8</sub>-<em>sn</em>-<wbr/>glycero-3-PC

1-Stearoyl-2-Arachidonoyl-d8sn–glycero-3-PC

CAT N°: 10009431
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From 82.00 69.70

1-Stearoyl-2-arachidonoyl-d8-sn-glycero-3-PC is intended for use as an internal standard for the quantification of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PC (Item No. 10009864) by GC- or LC-MS. 1-Stearoyl-2-arachidonoyl-sn-glycero-3-PC (SAPC) is a phospholipid containing stearic acid (Item No. 10011298) and arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607) at the sn-1 and sn-2 positions, respectively. It is a component of LDL and has been found in human stenotic aortic valves and atherosclerotic plaques.{17310,53168} Levels of SAPC are increased in the subepithelial invasive region compared to the superficial region of tumor tissue samples from patients with superficial-type pharyngeal squamous cell carcinoma.{53169} SAPC unilamellar vesicles have been used as substrates to quantify the activity of secretory phospholipase A2 (sPLA2) in the presence or absence of inhibitors.{53170} SAPC has also been used in the formation of lipid bilayers to study the effects of lipid composition on bilayer phase transitions.{53171}

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