Bezafibrate

Bezafibrate

CAT N°: 10009145
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From 20.00 17.00

Bezafibrate is a non-selective agonist of peroxisome proliferator-activated receptors (PPARs; EC50s = 50, 60, and 20 ?M for human PPAR?, PPAR?, and PPAR?, respectively).{10670} It reduces triglyceride levels and the size of lipid droplets in an oleic acid-induced HepaRG hepatocyte model of steatosis when used at a concentration of 25 ?M.{42456} Bezafibrate (10 mg/kg per day) reduces plasma VLDL and LDL mass and triglyceride and free fatty acid levels in a high-fructose plus lard diet-induced rat model of insulin resistance.{42937}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 2-[4-[2-[(4-chlorobenzoyl)amino]ethyl]phenoxy]-2-methyl-propanoic acid
  • Correlated keywords
    • Bezalip Bezatrol Difaterol BM15075 Befizal Bezatol Cedur nonselective PPAR-? ? ? lipoprotein FFA FA Hepa-RG
  • Product Overview:
    Bezafibrate is a non-selective agonist of peroxisome proliferator-activated receptors (PPARs; EC50s = 50, 60, and 20 ?M for human PPAR?, PPAR?, and PPAR?, respectively).{10670} It reduces triglyceride levels and the size of lipid droplets in an oleic acid-induced HepaRG hepatocyte model of steatosis when used at a concentration of 25 ?M.{42456} Bezafibrate (10 mg/kg per day) reduces plasma VLDL and LDL mass and triglyceride and free fatty acid levels in a high-fructose plus lard diet-induced rat model of insulin resistance.{42937}

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