CAY10573

CAY10573

CAT N°: 10008846
Price:

From 66.00 56.10

The peroxisome proliferator-activated receptors (PPARs) are lipid-activated transcription factors often used as drug targets for the treatment of metabolic disorders. CAY10573 is a PPAR agonist that displays potent binding at PPAR?, ?, and ? with IC50 values of 113, 50, and 223 nM, respectively. It potently transactivates PPAR?, ?, and ? with EC50 values of 8, 70, and 500 nM, respectively.{14166} CAY10573 demonstrates stronger binding and functional activity for PPAR? than the antidiabetic compound rosiglitazone (IC50 = 92 nM; EC50 = 220 nM).{14166}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 5-[3-[(6-benzoyl-1-propyl-2-naphthalenyl)oxy]propoxy]-1H-indole-1-acetic acid
  • Correlated keywords
    • PPARs rosiglitazone diabetes PPAR? PPAR? PPAR?
  • Product Overview:
    The peroxisome proliferator-activated receptors (PPARs) are lipid-activated transcription factors often used as drug targets for the treatment of metabolic disorders. CAY10573 is a PPAR agonist that displays potent binding at PPAR?, ?, and ? with IC50 values of 113, 50, and 223 nM, respectively. It potently transactivates PPAR?, ?, and ? with EC50 values of 8, 70, and 500 nM, respectively.{14166} CAY10573 demonstrates stronger binding and functional activity for PPAR? than the antidiabetic compound rosiglitazone (IC50 = 92 nM; EC50 = 220 nM).{14166}

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