20-<wbr/>HETE Ethanolamide

20-HETE Ethanolamide

CAT N°: 10008602
Price:

348.00 295.80

Arachidonoyl ethanolamide (AEA) is an endogenous lipid neurotransmitter with cannabinergic activity, binding both the central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors.{2713,14062} Fatty acid amide hydrolase (FAAH) is the enzyme responsible for the hydrolysis and inactivation of AEA.{13132} Metabolism of AEA by cyclooxygenase-2, leading to formation of prostaglandin ethanolamides, and by lipoxygenases has also been documented.{12168} 20-HETE ethanolamide is a potential cytochrome P450 metabolite of arachidonoyl ethanolamide, which may be particularly relevant under conditions of fatty acid amide hydrolase inhibition. Evidence for the formation of 20-HETE ethanolamide in vivo has not been documented.

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