Prostaglandin D<sub>2</sub> methyl ester

Prostaglandin D2 methyl ester

CAT N°: 10008385
Price:

From 65.00 55.25

Prostaglandin D2 (PGD2) is the major eicosanoid product of mast cells and is produced in large quantities by hematopoietic PGD synthase during allergic and asthmatic anaphylaxis.{416} It causes vasodilation, flushing, hypotension, and is an inhibitor of platelet aggregation.{416,580} Prostaglandin D2 methyl ester (PGD2 methyl ester) is a more lipid-soluble, cell-permeable prodrug form of PGD2.{14117} It binds to the human and mouse PGD2 receptors (DP1 and CRTH2/DP2) with 5-10 fold lower affinity than PGD2.{11494}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 9?,15S-dihydroxy-11-oxo-prosta-5Z,13E-dien-1-oic acid, methyl ester
  • Correlated keywords
    • esters prodrug H-PGDS synthases platelets aggregation mast cells hematopoietic allergic allergy asthmatic anaphylaxis vasodilation hypotension inhibits inhibitors inhibition brain b-trace .beta.-trace betatrace sleep prostaglandins
  • Product Overview:
    Prostaglandin D2 (PGD2) is the major eicosanoid product of mast cells and is produced in large quantities by hematopoietic PGD synthase during allergic and asthmatic anaphylaxis.{416} It causes vasodilation, flushing, hypotension, and is an inhibitor of platelet aggregation.{416,580} Prostaglandin D2 methyl ester (PGD2 methyl ester) is a more lipid-soluble, cell-permeable prodrug form of PGD2.{14117} It binds to the human and mouse PGD2 receptors (DP1 and CRTH2/DP2) with 5-10 fold lower affinity than PGD2.{11494}

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