Sphingosine (d18:1)

Sphingosine (d18:1)

CAT N°: 10007907
Price:

From 66.00 56.10

Sphingosine (d18:1) is formed primarily from the breakdown of ceramide.{13592} Sphingosine inhibits protein kinase C and phosphatidic acid phosphohydrolase, whereas it activates phospholipase D and diacylglycerol (DAG) kinase.{13592} Phosphorylation of sphingosine by sphingosine kinases 1 and 2 (SPHK 1, SPHK 2) produces sphingosine-1-phosphate, a potent bioactive lipid that exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis.{11895,12477,10628}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 2S-amino-4E-octadecene-1,3R-diol
  • Correlated keywords
    • Sphingosines S1P sphingosine-1-phosphates kinases SPHK1 SPHK2 Proliferation cancers inhibits inhibitors inhibition ceramides DAG diacylglycerols cells phophorylation morphogenesis SK1 sphingolipids SK2 anti-proliferative
  • Product Overview:
    Sphingosine (d18:1) is formed primarily from the breakdown of ceramide.{13592} Sphingosine inhibits protein kinase C and phosphatidic acid phosphohydrolase, whereas it activates phospholipase D and diacylglycerol (DAG) kinase.{13592} Phosphorylation of sphingosine by sphingosine kinases 1 and 2 (SPHK 1, SPHK 2) produces sphingosine-1-phosphate, a potent bioactive lipid that exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis.{11895,12477,10628}

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