17?-Estradiol

17?-Estradiol

CAT N°: 10006315
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Estrogens direct the development of the female genotype in embryogenesis and at puberty. 17?-Estradiol is the major estrogen secreted by the premenopausal ovary. It is synthesized from testosterone primarily in the ovarian granulosa cells and placenta, but small amounts can be produced in the adrenal gland.{8343,8342} Plasma 17?-estradiol levels increase gradually between days 1-7 of the menstrual cycle followed by a sharp increase to a peak value of about 300 pg/ml on day 12, just prior to ovulation.{8458,1594}

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