9(Z),11(E)-Conjugated Linoleic Acid (sodium salt)

9(Z),11(E)-Conjugated Linoleic Acid (sodium salt)

CAT N°: 31552
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From 176.00 149.60

9(Z),11(E)-Conjugated linoleic acid is an isomer of linoleic acid (Item Nos. 90150 | 90150.1 | 21909) that has been found in beef and milk fat.{6849} It binds to peroxisome proliferator-activated receptor ? (PPAR?; IC50 = 140 nM) and activates the receptor in a reporter assay using COS-1 cells expressing mouse PPAR? when used at a concentration of 100 µM.{15462} 9(Z),11(E)-Conjugated linoleic acid inhibits TNF-?-induced GLUT4 expression and increases insulin-stimulated glucose transport in 3T3-L1 adipocytes.{59110} Dietary administration of 9(Z)11(E)-conjugated linoleic acid reduces serum fasting glucose, insulin, and triglyceride levels and decreases white adipose tissue macrophage infiltration in ob/ob mice. It also increases body weight gain and body fat in weanling mice.{10568} [Matreya, LLC. Catalog No. 1278]

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