9-<wbr/><em>cis</em>-<wbr/>Retinoic Acid

9-cis–Retinoic Acid

CAT N°: 14587
Price:

74.00 62.90

9-cis-Retinoic acid is a natural metabolite of vitamin A, derived from the intermediate all-trans retinoic acid (Item No. 11017).{23078} It potently activates all isoforms of retinoic acid receptor (RAR) (Ki = 0.5-27 nM) as well as retinoid X receptor (RXR) isoforms (Ki = 3.8-12 nM).{23075,23076} RAR heterodimerizes with RXR, while RXR can homodimerize as well as heterodimerize with numerous partners in addition to RAR, thus allowing 9-cis-retinoic acid to evoke a wide range of effects.{23079,23078}

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