24(S),25-epoxy Cholesterol
24(S),25-epoxy Cholesterol
24(S),25-epoxy Cholesterol is an oxysterol and the most abundant oxysterol in mouse ventral midbrain.{43943} It activates liver X receptors (LXRs)...
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8-iso-15-keto Prostaglandin F2? (8-iso-15-keto PGF2?) is a metabolite of the isoprostane 8-iso PGF2? in rabbits, monkeys, and humans. 8-isoprostane (8-iso PGF2?) is a prostaglandin-like product of non-specific lipid peroxidation.{320} In both humans and monkeys, exogenously infused 8-iso PGF2? is converted primarily to metabolites having 2 or 4 carbon atoms removed from the top side chain by ?-oxidation.{6907} A similar pattern is observed when tritiated 8-iso PGF2? is infused into rabbits.{11209} Early in the infusion (within 1-2 minutes) 8-iso -15-keto PGF2? was a major component of the metabolite profile, which was comprised mostly of unmetabolized 8-iso PGF2?. 8-iso -15-keto PGF2? is a vasoconstrictor when tested on the rat isolated thoracic aorta, acting via the TP (thromboxane) receptor.{11221}
Territorial Availability: Available through Bertin Technologies only in France
| Size | 1 mg, 100 µg, 500 µg |
|---|---|
| Shipping | dry ice |
| CAS number | 191919-01-4 |
| Molecular formula | C20H32O5 |
| Smiles | O[C@@H]1[C@@H](C/C=CCCCC(O)=O)[C@@H](/C=C/C(CCCCC)=O)[C@H](O)C1, O[C@@H]1[C@@H](C/C=CCCCC(O)=O)[C@@H](/C=C/C(CCCCC)=O)[C@H](O)C1, O[C@@H]1[C@@H](C/C=CCCCC(O)=O)[C@@H](/C=C/C(CCCCC)=O)[C@H](O)C1 |
| Molecular weight | 352,5 |
| Custom code | 2937.50 |
| Formulation | A solution in methyl acetate |
| Purity | ≥95% |
| UNSPSC code | 12352100 |
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