6-Paradol

6-Paradol

CAT N°: 27554
Price:

From 146.00 124.10

6-Paradol is a phenolic ketone that has been found in ginger (Z. officinale) and has diverse biological activities, including antioxidant, anti-inflammatory, and anti-hyperglycemic properties.{50301,50302,50303} It inhibits hydrogen peroxide-induced oxidation of cell-free calf thymus DNA when used at a concentration of 100 ?M.{50301} In vitro, 6-paradol (10 ?g/ml) inhibits LPS-induced nitric oxide (NO), IL-6, and TNF-? production by mouse BV-2 microglia.{50302} In vivo, 6-paradol (6.75 mg/kg per day) lowers blood glucose levels in an oral glucose tolerance test (OGTT) and inhibits weight-gain in a mouse model of high-fat diet-induced obesity.{50303}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 1-(4-hydroxy-3-methoxyphenyl)-3-decanone
  • Correlated keywords
    • 1400-74-4 [6]-Gingerone (6) Zingiber antiinflammatory anti-oxidant antihyperglycemic H2O2 IL6 TNF? BV2
  • Product Overview:
    6-Paradol is a phenolic ketone that has been found in ginger (Z. officinale) and has diverse biological activities, including antioxidant, anti-inflammatory, and anti-hyperglycemic properties.{50301,50302,50303} It inhibits hydrogen peroxide-induced oxidation of cell-free calf thymus DNA when used at a concentration of 100 ?M.{50301} In vitro, 6-paradol (10 ?g/ml) inhibits LPS-induced nitric oxide (NO), IL-6, and TNF-? production by mouse BV-2 microglia.{50302} In vivo, 6-paradol (6.75 mg/kg per day) lowers blood glucose levels in an oral glucose tolerance test (OGTT) and inhibits weight-gain in a mouse model of high-fat diet-induced obesity.{50303}

We also advise you