6α-Prostaglandin I1
6α-Prostaglandin I1
6α-Prostaglandin I1 (6α-PGI1) is a stable Prostaglandin I2 (PGI2) analog resistant to hydrolysis in aqueous solutions. 6α-PGI1 promotes cyclic AMP...
€95.00 – €750.00
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From €95.00 €80.75
From €95.00 €80.75
6β-PGI1 is a stable PGI2 analog resistant to hydrolysis in aqueous solutions. 6β-PGI1 has a much longer half-life than PGI2, but a greatly reduced molar potency for receptor mediated function. 6β-PGI1 has a Kact for adenylate cyclase in NCB-20 cells of 4.2 µM compared with 18 nM for PGI2. The potency for vasodilation and inhibition of platelet aggregation is about 1% of PGI2.{509,1926}
Territorial Availability: Available through Bertin Technologies only in France
| Size | 1 mg, 10 mg, 5 mg |
|---|---|
| Shipping | dry ice |
| CAS Number | 62770-50-7 |
| Molecular Formula | C20H34O5 |
| SMILES | CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)C[C@H]2[C@@H]1C[C@@](CCCCC(O)=O)([H])O2 |
| Molecular Weight | 354,5 |
| Formulation | A crystalline solid |
| Purity | ≥99% |
| Custom Code | 2937.50 |
| UNSPSC code | 12352100 |
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6α-Prostaglandin I1 (6α-PGI1) is a stable Prostaglandin I2 (PGI2) analog resistant to hydrolysis in aqueous solutions. 6α-PGI1 promotes cyclic AMP...
Prostaglandin I2 (PGI2) is an unstable cyclooxygenase metabolite detected first in vascular endothelial cells.{502,443,933} It elevates platelet cAMP and is...
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