5,8,11-<wbr/>Eicosatriynoic Acid

5,8,11-Eicosatriynoic Acid

CAT N°: 90200
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From 128.00 108.80

5,8,11-ETI is a nonselective inhibitor of lipoxygenases. It inhibits 12-LO in human platelets with an ID50 value of 24 µM.{66} 5,8,11-ETI also inhibits A23187 and L-cysteine induced LTC4 biosynthesis in mouse mastocytoma cells with an ID50 value of 5 µM.{650} At higher concentrations, 5,8,11-ETI also inhibits cyclooxygenases (ID50 = 340 µM).{66}

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