5-<em>trans</em> Fluprostenol isopropyl ester

5-trans Fluprostenol isopropyl ester

CAT N°: 16777
Price:

From 132.00 112.20

Travoprost is the Alcon trade name for fluprostenol isopropyl ester, an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug.{8839,9613} Fluprostenol isopropyl ester is a prodrug which is converted by esterase enzymatic activity in the cornea to yield the corresponding free acid.{8839} 5-trans Fluprostenol isopropyl ester (5-trans Travoprost) is an impurity that is routinely found in bulk preparations of fluprostenol isopropyl ester in amounts ranging from 1-3%. The pharmacology of 5-trans travoprost has not been studied extensively to date.

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • (5E)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]cyclopentyl]-5-heptenoic acid, 1-methylethyl ester
  • Correlated keywords
    • prostaglandins ocular hypotensive cornea prodrugs 5-trans-fluprostenol esters intraocular ophthalmology glaucoma
  • Product Overview:
    Travoprost is the Alcon trade name for fluprostenol isopropyl ester, an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug.{8839,9613} Fluprostenol isopropyl ester is a prodrug which is converted by esterase enzymatic activity in the cornea to yield the corresponding free acid.{8839} 5-trans Fluprostenol isopropyl ester (5-trans Travoprost) is an impurity that is routinely found in bulk preparations of fluprostenol isopropyl ester in amounts ranging from 1-3%. The pharmacology of 5-trans travoprost has not been studied extensively to date.

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