5-<wbr/>Octyl-?-<wbr/>ketoglutarate

5-Octyl-?-ketoglutarate

CAT N°: 16105
Price:

136.00 115.60

In addition to its role in the Krebs cycle, ?-ketoglutarate (2-oxoglutarate) has roles as a substrate or modulator of enzymes. 5-Octyl-?-ketoglutarate, also known as ?-ketoglutarate octyl ester, is a stable, cell-permeable molecule that generates free ?-ketoglutarate upon hydrolysis of the ester bond by cytoplasmic esterases.{21289} It is used in experiments to increase levels of intracellular ?-ketoglutarate.{21289} 5-Octyl-?-ketoglutarate has been shown to modulate a variety of enzymes and signaling pathways, particularly in the context of glycolysis, hypoxia, and cancer.{21289,26774,27744,27745,26069}

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