5-hydroxy-N<sup>?</sup>-methyl Tryptamine (oxalate)

5-hydroxy-N?-methyl Tryptamine (oxalate)

CAT N°: 20047
Price:

From 122.00 103.70

5-hydroxy-N?-methyl Tryptamine is a metabolite of serotonin (5-HT; Item No. 14332) in humans that has also been found in plants.{48185,31973,42693} It is an agonist of the 5-HT receptor subtype 5-HT7 (IC50 = 23 pM in a radioligand binding assay).{31973} 5-hydroxy-N?-methyl Tryptamine increases intracellular cyclic AMP production in HEK293 cells expressing 5-HT7 (EC50 = 22 nM). It inhibits serotonin uptake in HEK293 cells expressing human serotonin transporters (IC50 = 490 nM). Elevated levels of urinary 5-hydroxy-N?-methyl tryptamine have been found in patients with schizophrenia, depression, and epilepsy.{48185}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 3-[2-(methylamino)ethyl]-1H-indol-5-ol, ethanedioate
  • Correlated keywords
    • 1134-01-6 methyltryptamine 5HT 7 5HT7 HEK-293 methyl5HT methylserotonin
  • Product Overview:
    5-hydroxy-N?-methyl Tryptamine is a metabolite of serotonin (5-HT; Item No. 14332) in humans that has also been found in plants.{48185,31973,42693} It is an agonist of the 5-HT receptor subtype 5-HT7 (IC50 = 23 pM in a radioligand binding assay).{31973} 5-hydroxy-N?-methyl Tryptamine increases intracellular cyclic AMP production in HEK293 cells expressing 5-HT7 (EC50 = 22 nM). It inhibits serotonin uptake in HEK293 cells expressing human serotonin transporters (IC50 = 490 nM). Elevated levels of urinary 5-hydroxy-N?-methyl tryptamine have been found in patients with schizophrenia, depression, and epilepsy.{48185}

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