5-fluoro Orotic Acid (hydrate)

5-fluoro Orotic Acid (hydrate)

CAT N°: 17318
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From 91.00 77.35

5-fluoro Orotic acid (5-FOA) is used to detect URA3 gene expression in yeast molecular genetic constructs.{28301} Yeast with an active URA3 gene, which encodes orotidine-5′-monophosphate decarboxylase, converts 5-FOA to fluorodeoxyuridine, which is toxic to cells. Resistant strains of yeast that carry a mutation in the URA3 gene grow in the presence of 5-FOA if the media is supplemented with uracil.

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