5β,6β-epoxy Cholestanol

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From 74.00467.00

5β,6β-epoxy Cholestanol is an oxidative metabolite of cholesterol that is formed via radical and non-radical oxidation of cholesterol at the 5,6-double bond.{13448,41987} It induces release of lactate dehydrogenase (LDH) and apoptosis in macrophage-differentiated U937 cells.{39949} 5β,6β-epoxy Cholestanol has been found in human fatty streaks and advanced atherosclerotic lesions but is not present in normal aortic tissue.{39950}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 5β,6β-epoxy-cholestan-3β-ol
  • Correlated keywords
    • 133331-00-7 U-937 NSC148940
  • Product Overview:
    5β,6β-epoxy Cholestanol is an oxidative metabolite of cholesterol that is formed via radical and non-radical oxidation of cholesterol at the 5,6-double bond.{13448,41987} It induces release of lactate dehydrogenase (LDH) and apoptosis in macrophage-differentiated U937 cells.{39949} 5β,6β-epoxy Cholestanol has been found in human fatty streaks and advanced atherosclerotic lesions but is not present in normal aortic tissue.{39950}

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