4-Thiouridine

4-Thiouridine

CAT N°: 16373
Price:

From 55.00 46.75

4-Thiouridine (4-SU) is a photoactivatable ribonucleoside analog that is widely used for RNA analysis, including short-range RNA-RNA crosslinking and nascent RNA labeling.{26731,26729,26732} The crosslinking thio moiety is attached directly to the nucleotide base, thus 4-SU differs from uridine only by a single sulfur substitution. This offers the advantage of incorporating into an RNA chain with minimal structural perturbation and with similar base-pairing properties, reducing the likelihood that substitution will impair RNA interactions or activities.{26732}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 4-thio-uridine
  • Correlated keywords
    • 17676-63-0 crosslinking cross linking analogs photoreactives ribonucleotides RNA molecular biology nucleotides reactive probes 4 four thiouridine photoactivatable analysis short-range shorts ranges RNA-RNA nascent labeling impairs interactions activities NSCs 518132 NSC518132 NSC-518132 4SU SUs
  • Product Overview:
    4-Thiouridine (4-SU) is a photoactivatable ribonucleoside analog that is widely used for RNA analysis, including short-range RNA-RNA crosslinking and nascent RNA labeling.{26731,26729,26732} The crosslinking thio moiety is attached directly to the nucleotide base, thus 4-SU differs from uridine only by a single sulfur substitution. This offers the advantage of incorporating into an RNA chain with minimal structural perturbation and with similar base-pairing properties, reducing the likelihood that substitution will impair RNA interactions or activities.{26732}

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