4-<wbr/>Methylbenzylidene camphor

4-Methylbenzylidene camphor

CAT N°: 13840
Price:

From 180.00 153.00

4-Methylbenzylidene camphor is an ultraviolet light blocker used in cosmetics and sunscreen preparations that also has estrogenic activities.{20419,20420} It has estrogenic activity in fish and in mammals, binding competitively to estrogen receptors and stimulating transactivation.{20419} In addition to reducing receptor sensitivity to estradiol, 4-MBC directs dose-dependent changes in the expression of estrogen receptor subtypes, progesterone receptor, and androgen receptor.{20419,20420} This results in changes in reproductive organ and brain development in both males and females.{20419,20420} When applied topically, it is absorbed systemically and can be detected in urine.{20421}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 1,7,7-trimethyl-3-[(4-methylphenyl)methylene]-bicyclo[2.2.1]heptan-2-one
  • Correlated keywords
    • 38102-62-4 84055-65-2 parsol 5000 4MBC 4 MBC sunscreen cosmetics UV lights estrogen estradiol endocrine disruptors androgen progesterone hormones genes expressions development reproduction ultraviolet
  • Product Overview:
    4-Methylbenzylidene camphor is an ultraviolet light blocker used in cosmetics and sunscreen preparations that also has estrogenic activities.{20419,20420} It has estrogenic activity in fish and in mammals, binding competitively to estrogen receptors and stimulating transactivation.{20419} In addition to reducing receptor sensitivity to estradiol, 4-MBC directs dose-dependent changes in the expression of estrogen receptor subtypes, progesterone receptor, and androgen receptor.{20419,20420} This results in changes in reproductive organ and brain development in both males and females.{20419,20420} When applied topically, it is absorbed systemically and can be detected in urine.{20421}

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