4-(2,2,3-Trimethylcyclopentyl)butanoic Acid

4-(2,2,3-Trimethylcyclopentyl)butanoic Acid

CAT N°: 19606
Price:

From 54.00 45.90

4-(2,2,3-Trimethylcyclopentyl)butanoic acid is an orthosteric, insurmountable antagonist of the human bitter taste receptors hTAS2R31 and hTAS2R43.{32346} It prevents the activation of hTAS2R31 by saccharin and acesulfame K in cells with IC50 values of 7.9 and 2.4 µM, respectively.{32346} In human sensory trials, 4-(2,2,3-trimethylcyclopentyl)butanoic acid significantly reduced the bitter flavor associated with these two artificial sweeteners.{32346}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 2,2,3-trimethyl-cyclopentanebutanoic acid
  • Correlated keywords
    • hTAS2R31 hTAS2R43 GIV-3727 orthosteric bitter taste
  • Product Overview:
    4-(2,2,3-Trimethylcyclopentyl)butanoic acid is an orthosteric, insurmountable antagonist of the human bitter taste receptors hTAS2R31 and hTAS2R43.{32346} It prevents the activation of hTAS2R31 by saccharin and acesulfame K in cells with IC50 values of 7.9 and 2.4 µM, respectively.{32346} In human sensory trials, 4-(2,2,3-trimethylcyclopentyl)butanoic acid significantly reduced the bitter flavor associated with these two artificial sweeteners.{32346}

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