3,3',5-<wbr/>Triiodo-<wbr/>L-<wbr/>thyronine (sodium salt hydrate)

3,3′,5-Triiodo-L-thyronine (sodium salt hydrate)

CAT N°: 16028
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From 66.00 56.10

3,3′,5-Triiodo-L-thyronine (T3) is a thyroid hormone.{61095} It is produced by 5′-monodeiodination of the prohormone thyroxine (T4) in various tissues, including liver and kidney. T3 is an agonist of thyroid hormone receptors TR? and TR? (Kis = 2.3 nM for both) that modulates diverse biological properties, including metabolism, cardiac function, growth, and redox signaling.{27008,27007,27010,27009} It also functions as an inhibitor of L-type amino acid transporter 1 (LAT1), inhibiting LAT1-mediated leucine uptake in HEK293 cells when used at a concentration of 10 µM.{59277}

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