2C-<wbr/>B (hydro<wbr>chloride)

2C-B (hydrochloride)

CAT N°: 11734
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A series of 2,5-dimethoxyphenethylamines, collectively referred to as 2Cs, have psychoactive effects.{20685,20772} The most effective 2C compounds are substituted at the 4 position of the aromatic ring; many are scheduled as illegal substances.{19963,19758} 2C-B is described formally as 4-bromo-2,5-dimethoxy phenethylamine. This hallucinogenic designer drug activates the serotonin receptor 5-HT2C (pEC50 = 6.8 for arachidonic acid release).{20772} Its metabolism has been reviewed.{19963} LC-MS/MS screening methods for identifying this compound in serum have been developed.{21281} 2C-B is regulated as a Schedule I compound in the United States. This product is intended for forensic and research purposes.

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