24(R)-<wbr/>hydroxy Cholesterol

24(R)-hydroxy Cholesterol

CAT N°: 10217
Price:

From 74.00 62.90

24(S)-hydroxy Cholesterol is a side-chain substituted oxysterol that is generated from the action of CYP46 on cholesterol found in the brain and plays an important role in cholesterol homeostasis.{15406} 24(R)-hydroxy Cholesterol is a synthetic enantiomer of 24(S)-hydroxy cholesterol that activates LXR? and LXR? nuclear receptors with slightly reduced potency (EC50 = 7 and 4 ?M, respectively) compared to the natural isomer (EC50 = 4 and 3 ?M, respectively).{15406,25539}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • cholest-5-ene-3?,24R-diol
  • Correlated keywords
    • 24(S)-hydroxy Cholesterol 24(S)-OH side-chain substitution oxysterols cholesterol brain homeostasis LXR? LXR? LXR a b alpha beta a b .alpha. .beta. LXR-a LXR-a LXR-alpha LXR-.alpha. LXR-b LXR-b LXR-beta LXR-.beta. synthetic enantiomer brain-derived derived OH hydroxycholesterol
  • Product Overview:
    24(S)-hydroxy Cholesterol is a side-chain substituted oxysterol that is generated from the action of CYP46 on cholesterol found in the brain and plays an important role in cholesterol homeostasis.{15406} 24(R)-hydroxy Cholesterol is a synthetic enantiomer of 24(S)-hydroxy cholesterol that activates LXR? and LXR? nuclear receptors with slightly reduced potency (EC50 = 7 and 4 ?M, respectively) compared to the natural isomer (EC50 = 4 and 3 ?M, respectively).{15406,25539}

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