2''-O-Galloyl<wbr/>hyperin

2”-O-Galloylhyperin

CAT N°: 29086
Price:

From 55.00 46.75

2”-O-Galloylhyperin is a natural flavonoid that has been found in P. incarnata and has diverse biological activities, including antioxidant, anti-inflammatory, hepatoprotective, and transporter-inhibiting properties.{53103,53104,53105} It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805) and ABTS (Item No. 27317) radicals (IC50s = 3 and 3.5 ?M, respectively).{53103} It also inhibits human organic anion transporting polypeptide 1B1 (OATP1B1; IC50 = 19 ?M in HEK293 cells).{53104} 2”-O-Galloylhyperin (15 ?M) decreases LPS-induced IL-6 and TNF-? cytokine production from mouse RAW 264.7 macrophages.{53105} It also decreases LPS-induced mortality and liver damage in a mouse model of septic shock when administered at a dose of 50 mg/kg.

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[[2-O-(3,4,5-trihydroxybenzoyl)-?-D-galactopyranosyl]oxy]-4H-1-benzopyran-4-one
  • Correlated keywords
    • 53745-13-4 56552-82-0 Galloylhyperoside Galloyl-hyperoside Quercetin 3-?-galactoside-2”-gallate Passiflora anti-oxidant antiinflammatory hepato-protective OATP-1B1 TNF? IL6 Lipopolysaccharide
  • Product Overview:
    2”-O-Galloylhyperin is a natural flavonoid that has been found in P. incarnata and has diverse biological activities, including antioxidant, anti-inflammatory, hepatoprotective, and transporter-inhibiting properties.{53103,53104,53105} It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805) and ABTS (Item No. 27317) radicals (IC50s = 3 and 3.5 ?M, respectively).{53103} It also inhibits human organic anion transporting polypeptide 1B1 (OATP1B1; IC50 = 19 ?M in HEK293 cells).{53104} 2”-O-Galloylhyperin (15 ?M) decreases LPS-induced IL-6 and TNF-? cytokine production from mouse RAW 264.7 macrophages.{53105} It also decreases LPS-induced mortality and liver damage in a mouse model of septic shock when administered at a dose of 50 mg/kg.

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