2-Iodomelatonin

2-Iodomelatonin

CAT N°: 19711
Price:

74.00 62.90

2-iodomelatonin is a potent agonist of melatonin receptor 1 (MT1; Ki = 28 pM) that is 5-fold selective for MT1 over MT2.{26017,26021} It inhibits forskolin-stimulated cAMP production in CHO cells expressing human MT1 30-fold more potently than melatonin (Item No. 14427) with an EC50 value of 11 pM. 2-iodomelatonin has been used to characterize the role of MT1 in melatonin-mediated signaling.{40764,40765}

We also advise you