2-<wbr/>Hydroxypropyl-<wbr/>?-<wbr/>cyclodextrin

2-Hydroxypropyl-?-cyclodextrin

CAT N°: 16169
Price:

From 49.00 41.65

2-Hydroxypropyl-?-cyclodextrin (HP-?-CD) is a cyclic oligosaccharide containing seven D-(+)-glucopyranose units that is widely used to improve the aqueous solubility of various compounds, especially those containing a phenyl group.{26620,26621,23432} The circular arrangement of its glucose units produces a torus-shaped ring configuration in which the CH2 groups and ether linkages of the molecule face the hollow interior, resulting in a nonpolar, hydrophobic cavity and a polar, hydrophilic exterior. When combined in solution with other compounds, the nonpolar aromatic portions of that compound interact with the nonpolar interior of the HP-?-CD molecule, thus isolating the aromatic portion of the molecule from the water and thereby increasing its aqueous solubility.{26620,21228} HP-?-CD is a mixture containing HP-?-CD with variable hydroxypropyl group substitutions.

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 2-hydroxypropyl ethers ?-cyclodextrin
  • Correlated keywords
    • complexation improved aqueous solubility cyclic oligosaccharides drugs delivery bioavailability HPs ? CDs HP?CDs glucopyranose D-(+)-glucopyranose improves compounds phenyls groups rings configurations circular glucose units torus shaped torus-shaped groups ethers linkages hollow interiors nonpolar non polar non-polar hydrophobic cavity cavities hydrophilic exteriors solutions molecules isolates isolation isolated aromatics water increases increased 94035-02-6 (2-hydroxypropyl)-?-cyclodextrin hydroxypropyl cylclodextrin discovery
  • Product Overview:
    2-Hydroxypropyl-?-cyclodextrin (HP-?-CD) is a cyclic oligosaccharide containing seven D-(+)-glucopyranose units that is widely used to improve the aqueous solubility of various compounds, especially those containing a phenyl group.{26620,26621,23432} The circular arrangement of its glucose units produces a torus-shaped ring configuration in which the CH2 groups and ether linkages of the molecule face the hollow interior, resulting in a nonpolar, hydrophobic cavity and a polar, hydrophilic exterior. When combined in solution with other compounds, the nonpolar aromatic portions of that compound interact with the nonpolar interior of the HP-?-CD molecule, thus isolating the aromatic portion of the molecule from the water and thereby increasing its aqueous solubility.{26620,21228} HP-?-CD is a mixture containing HP-?-CD with variable hydroxypropyl group substitutions.

We also advise you