2'-Deoxy<wbr/>cytidine (hydro<wbr/>chloride)

2′-Deoxycytidine (hydrochloride)

CAT N°: 30125
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From 48.00 40.80

2’-Deoxycytidine is a deoxyribonucleoside composed of a deoxyribose sugar and a cytosine base.{48688} It is phosphorylated by deoxycytidine kinase in the cytosol or thymidine kinase 2 (TK2) in mitochondria to form deoxycytidine monophosphate (dCMP; Item No. 29340).{48673,48672} Oral administration of 2’-deoxycytidine in combination with deoxythymidine delays disease onset and increases lifespan in a Tk2 H126N knock-in (Tk2-/-) mouse model of TK2 deficiency.{48673}

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