Histone H2A (Xenopus, recombinant)
Histone H2A (Xenopus, recombinant)
Histone H2A is a core histone that forms a dimer with histone H2B.{46631} Two histone H2A/H2B dimers form an octameric...
€818.00
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From €151.00 €128.35
From €151.00 €128.35
2-Chloroadenosine 5-triphosphate (2-chloro ATP) is an adenine nucleotide and analog of ATP (Item No. 14498).{62566,62567} It is an antagonist of the purinergic P2Y1 receptor, inhibiting intracellular calcium mobilization induced by ADP (Item No. 21121) in Jurkat cells expressing the human receptor (Ki = 2.3 µM).{62568} 2-chloro ATP is an agonist of purinergic P2X receptors, inducing inward currents in HEK293 cells expressing the human bladder smooth muscle or rat PC12 forms of the receptor (EC50s = 0.5 and 2.5 µM, respectively).{62569} It induces relaxation of precontracted isolated guinea pig taenia caeci strips in a concentration-dependent manner.{62566} It has been used to study the substrate specificity of cyclic nucleotide-dependent protein kinases, such as protein kinase A (PKA) and PKG.{62567}
Territorial Availability: Available through Bertin Technologies only in France
| Size | 1 mg, 500 µg |
|---|---|
| Shipping | dry ice |
| CAS number | 301334-89-4 |
| Molecular formula | C10H11ClN5O13P3 • 4Na |
| Smiles | O[C@H]1[C@](O[C@@H]([C@H]1O)COP(OP(OP([O-])([O-])=O)([O-])=O)([O-])=O)([H])N2C3=NC(Cl)=NC(N)=C3N=C2.[Na+].[Na+].[Na+].[Na+] |
| Molecular weight | 629,6 |
| Custom code | 2932.99 |
| Formulation | A solution in water |
| Purity | ≥95% |
| UNSPSC code | 12352100 |
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