2-<wbr/>Chloroadenosine

2-Chloroadenosine

CAT N°: 15612
Price:

From 48.00 40.80

2-Chloroadenosine (CADO) is a metabolically stable analog of adenosine that binds to adenosine A1, A2A, and A3 receptors with Ki values of 300, 80, and 1,900 nM, respectively.{19450} CADO has been used to activate adenosine receptors in the thalamus, generating anticonvulsive activity in a rat model of generalized seizures.{19452} It has also been used to induce bronchoconstrictor effects in a guinea pig model of asthma and to study cardiovascular responses in normotensive and hypertensive rats.{19453,19450}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 2-chloro-adenosine
  • Correlated keywords
    • adenosines analogs receptors agonist A1 A2a A3 anticonvulsant neurosciences asthma cardiovascular chloro anti-convulsant anti convulsant 2-Cl-Ade 2-chloro-D-adenosine antibiotics ATs 265B NSCs 36896 NSC-36896 NSC36896 2 two 2a a 1 3 one three thalamus rats models seizures induces bronchoconstrictors guinea pigs normotensive hypertensive
  • Product Overview:
    2-Chloroadenosine (CADO) is a metabolically stable analog of adenosine that binds to adenosine A1, A2A, and A3 receptors with Ki values of 300, 80, and 1,900 nM, respectively.{19450} CADO has been used to activate adenosine receptors in the thalamus, generating anticonvulsive activity in a rat model of generalized seizures.{19452} It has also been used to induce bronchoconstrictor effects in a guinea pig model of asthma and to study cardiovascular responses in normotensive and hypertensive rats.{19453,19450}

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